Micah Vandegrift, senior user experience (UX) strategist for the National Institutes of Health’s (NIH) All of Us Research Program, will give a Open Access Week 2022 keynote address at the University of Massachusetts Amherst. Vandegrift's virtual talk, “Open to Change: Possibilities and Probabilities,” addresses current opportunities at the intersection of climate change, open science, and community engagement, in light of the updated policy to make the results of taxpayer-supported research immediately available to the American public at no cost. Vandegrift will outline a possible case study informed by his experience and recent research, provide a foundation and a forecast, and answer questions following his talk.